Advances in understanding the correlation between multi-drug resistance gene and ulcerative colitis

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Recent advances in understanding ulcerative colitis.

Ulcerative colitis, one of the two main forms of inflammatory bowel disease, is characterized by inflammation of the large bowel with constant involvement of the rectum, and a possible continuous retrograde distribution up to the cecum. Typical macroscopic lesions are mucosal ulcerations, with immune cell infiltration and cryptic abscesses at histology. Ulcerative colitis usually manifests with...

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Multidrug resistance gene and its relationship to ulcerative colitis and immune status of ulcerative colitis.

We examined the relationship among the multidrug resistance (MDR1) gene product P-glycoprotein (P-gp), ulcerative colitis, and immune status under ulcerative colitis. MDR1 P-gp expression and interleukin-8 levels in ulcerative colitis were determined using immunohistochemistry and a double-antibody sandwich avidin-biotin complex-enzyme-linked immunosorbent assay, respectively. Nitric oxide cont...

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Drug Therapy in Ulcerative Colitis

The two primary types of inflammatory bowel disease (IBD) are ulcerative colitis (CU) and Crohn's disease (CD). These two diseases have many similarities and sometimes are difficult to distinguish from each other. However, there are several differences. UC is an inflammatory destructive disease of the large intestine characterized by motility and secretion disorders. Inflammation usually occurs...

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Advances in Ulcerative Colitis - Volume 3

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ژورنال

عنوان ژورنال: World Chinese Journal of Digestology

سال: 2009

ISSN: 2219-2859

DOI: 10.11569/wcjd.v17.i34.3530